This lesion may be accompanied by inflammation in the dermis. Skin Skin lesions are the characteristic feature of malignant atrophic papulosis. Cutaneous atrophy results from catabolic GC effects on keratinocytes and fibroblasts. By continuing you agree to the use of cookies. One study reported facial fullness (“moon facies”) in 13% of patients receiving 4–12 mg triamcinolone for up to 60 days. The secretory func-tion is reduced, and the skin surface dries. Purpura and easy bruising in GC-treated patients probably result from decreased vascular structural integrity. 2002. Bijlsma, in. Thus, patients often have both an infraorbital hollow and a tear trough concavity just below this. The Atlas functions best with JavaScript enabled but may used without JavaScript. High-risk locations are (1) the face, (2) neck, (3) axilla, (4) groin, (5) upper inner thighs, and (6) pretibial locations. Lupus panniculitis is one of the few panniculitides that can occur above the waist. A cushingoid appearance is very troubling to patients, but is uncommon at doses below the physiologic range. This results in a protuberance of tissue just below these folds giving a “double-bubble” appearance (Fig. For the tear trough itself, filler is best injected deep to the orbicularis muscle at the level of the periosteum (see Figs 4-7C & 4-13). ), periorbital augmentation should be attempted only by a skilled injector. Copyright © 2021 Elsevier B.V. or its licensors or contributors. In: Pathology of the Fischer Rat: Reference and Atlas (Boorman GA, Eustis SL, Elwell MR, Montgomery CA, MacKenzie WF, eds). Atrophic skin spots; Atrophic spots of skin; Clinical Information. Annular atrophic plaques of the skin is an uncommon condition described in 1967 by Christianson [1, 2]. Aside from residual scars on the right side of the forehead, there were no signs of facial atrophy, neurological abnormalities, exophthalmos or other skin lesions. Combinations of toxin and fillers in some areas can sometimes optimize results. Atlas Home »  The incidence of iatrogenic Cushing's syndrome is dose dependent and generally becomes evident after >1 month of GC therapy. We use cookies to help provide and enhance our service and tailor content and ads. Atrophy of the occipital cortex did not correspond to the presence of lesions in the optical pathway, probably because it is associated with many other pathways. A disorder characterized by the degeneration and thinning of the epidermis and dermis. For the infra-orbital hollow, filler is injected in a subcutaneous fat plane above the orbicularis muscle. Adnexal or follicular atrophy may correspond to the gross observation of alopecia. Vaginal atrophy occurs most often after menopause.For many women, vaginal atrophy not only makes intercourse painful but also leads to distressing urinary symptoms. Morphea is relatively uncommon and women are affected about three times as often as men. 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